2-(2,4-Dichlorophenyl)-3-[5-(3,5-dimethylphenyl)-1,3,4-thiadiazol-2-yl]thiazolidin-4-one
نویسندگان
چکیده
The title compound, C(19)H(15)Cl(2)N(3)OS(2), was synthesized by the reaction of N-(2,4-dichloro-phen-yl)-5-(3,5-dimethyl-phen-yl)-1,3,4-thia-diazol-2-amine and mercaptoacetic acid. The thia-zolidinone ring adopts a twist conformation. The 2,4-dichloro-phenyl ring is almost perpendicular to the thia-diazole ring, the dihedral angle being 82.8 (2)°. The 3,5-dimethyl-phenyl ring is nearly coplanar with the thia-diazole ring, the dihedral angle being 2.7 (2)°. An intramolecular C-H⋯N hydrogen bond is present.
منابع مشابه
(E)-5-(3,5-Dimethylphenyl)-N-[4-(methylsulfanyl)benzylidene]-1,3,4-thiadiazol-2-amine
The title compound, C(18)H(17)N(3)S(2), was synthesized by the reaction of 5-(3,5-dimethyl-phen-yl)-1,3,4-thia-diazol-2-amine and 4-(methyl-sulfan-yl)benzaldehyde. An intra-molecular C-H⋯S hydrogen bond results in the formation of a planar (r.m.s. deviation = 0.003 Å) five-membered ring. In the crystal structure, inter-molecular C-H⋯N hydrogen bonds link the mol-ecules to form layers parallel t...
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The title compound, C(20)H(22)Cl(2)N(3)O(4)PS, was synthesized by the reaction of N-(4-methoxy-benzyl-idene)-5-(2,4-dichloro-phenyl)-1,3,4-thia-diazol-2-amine and diethyl phosphite. In the crystal, inter-molecular C-H⋯O and N-H⋯O hydrogen bonds link the mol-ecules.
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The title compound, C(18)H(14)FN(3)O(2)S(2), was synthesized by the reaction of 5-(4-fluoro-phen-yl)-N-(4-methoxy-benzyl-idene)-1,3,4-thia-diazol-2-amine and mercaptoacetic acid. The thia-zolidinone ring adopts a twist conformation. The 4-methoxy-phenyl ring is almost perpendicular to the thia-diazole ring, making a dihedral angle of 88.4 (3)°. The 4-fluoro-phenyl ring is nearly coplanar with t...
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In the title compound, C(16)H(8)Cl(2)F(2)N(4)O(2)S, the thia-diazole ring makes dihedral angles of 24.94 (14) and 48.11 (14)°, respectively, with the dichloro- and difluoro-substituted benzene rings. An intra-molecular N-H⋯O hydrogen bond results in the formation of a planar (mean deviation 0.0091 Å) six-membered ring. In the crystal structure, mol-ecules form centrosymmetric dimers through pai...
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